central nervous system


Antidepressants help us understand why we get fatigued during exercise

In general, the term ‘fatigue’ is used to describe any exercise-induced decline in the ability of a muscle to generate force. To identify the causes of fatigue, it is common to examine two divisions of the body that might be affected during exercise. The central component of fatigue includes the […]


Fatigue-Related Pain From Distal Muscles Reduces Central Motor Drive Of Proximal Muscles Of The Same Limb

Understanding the mechanisms of fatigue provides insight into the limits of human exercise performance and diseases in which fatigue is a symptom that limits activity. Both peripheral and central mechanisms contribute to muscle fatigue. Central fatigue is defined as a progressive exercise-induced reduction in the ability to voluntarily activate a […]