serotonin


Antidepressants help us understand why we get fatigued during exercise

In general, the term ‘fatigue’ is used to describe any exercise-induced decline in the ability of a muscle to generate force. To identify the causes of fatigue, it is common to examine two divisions of the body that might be affected during exercise. The central component of fatigue includes the […]


Too much of a good thing? A new role for serotonin in the human spinal cord

Serotonin is one of the “feel good” neuromodulators floating around in the central nervous system, however, it doesn’t just play a role when it comes to our mood. Serotonin plays a very important role in transmitting impulses between nerve cells. More specifically, it affects the excitability of our motoneurones, the […]


Serotonin, Spasticity and Spinal Cord Injury (The Three S’s)

Immediately following a spinal cord injury (SCI) patients enter a state of areflexia and muscle weakness that is gradually replaced by the recovery of neuronal and network excitability leading to improvements in residual motor function over time as well as to the development of spasticity (i.e. involuntary muscle spasms). Spasticity […]