muscle fatigue


Why does motor performance decline with aging?

Populations in many countries are aging as the proportion of people over 65 years is projected to increase over the next 30-40 years. Aging however, is accompanied by a reduced ability to perform daily tasks such as walking, rising from a chair and climbing stairs, ultimately impacting independence of living. […]


Repetitive activity, fatigue and human motoneurones

Exercise induced muscle fatigue is a common experience for healthy people. It involves multiple changes in the nervous system such as changes at the spinal and supraspinal level (central fatigue) and changes in the muscle itself (peripheral fatigue). During a fatiguing maximal effort, the ability of the nervous system to […]


Interview: Professor Simon Gandevia talks about Motor Impairment

Ahead of the second annual Motor Impairment meeting, Simon Gandevia, Deputy Director of Neuroscience Research Australia, talks about Motor Impairment; what it is and what he and his colleagues at NeuRA are investigating as part of the NHMRC-funded program grant.    


More pain, less gain: Can painful, fatiguing exercise of one muscle impair the exercise performance of its neighbours?

We have all experienced the effects of muscle fatigue. Whether carrying groceries or luggage that extra bit further, playing sport or hitting it hard at the gym. For people with conditions such as multiple sclerosis, congestive heart failure, or peripheral vascular disease just going to collect the mail can be […]


Fatigue-Related Pain From Distal Muscles Reduces Central Motor Drive Of Proximal Muscles Of The Same Limb

Understanding the mechanisms of fatigue provides insight into the limits of human exercise performance and diseases in which fatigue is a symptom that limits activity. Both peripheral and central mechanisms contribute to muscle fatigue. Central fatigue is defined as a progressive exercise-induced reduction in the ability to voluntarily activate a […]